1/12/2024 0 Comments Retina art or the unretina art“As with all of its medicines, Genentech has taken a thoughtful and responsible approach to determining the price of Susvimo, and is committed to partnering with governments, regulatory and reimbursement authorities and non-governmental stakeholders to identify solutions that will help ensure its medicines are accessible for patients who need them,” Ms. That adds up to a first-year price of $17,250, which Genentech says is 26 percent less than the yearly price of monthly Lucentis injections. Refills will cost $8,000 every six months-the on-label interval. For the first six months, the price of Susvimo is $9,250, which includes the implanted device and medicine, Shirley Dang, senior manager of corporate relations at Genentech, tells Retina Specialist. That doesn’t even take into account Susvimo, which Genentech says it will price competitively with existing anti-VEGF platforms. With at least two more investigative Lucentis biosimilars and Outlook Therapeutics’ ophthalmic formulation of Avastin (bevacizumab) “hot on their heels,” and other anti-VEGF treatments in Phase III trials, “In five years we could have 10 or more manufacturers competing in this space,” Downs said. Byooviz, Samsung Bioepis-Biogen Lucentis biosimilar, would make four. Novartis’ Beovu (brolucizumab), approved in 2019, makes three. Downs said at the OIS meeting, meaning, of course, Genentech/Roche with Lucentis (ranibizumab) and Regeneron Pharmaceuticals with Eylea (aflibercept). “A couple of years ago there were only two competitors in terms of manufacturers in the anti-VEGF market in the United States,” Mr. Peter Downs, an author and analyst with Market Scope, a medical market data and analytics firm, gave that assessment during the OIS meeting last month. With the recent approvals of the Susvimo ranibizumab port delivery system and the Samsung Bioepis-Biogen Lucentis biosimilar, scheduled to launch next summer, the market for anti-VEGF therapies is about to enter a new era of heightened competition that will cause downward pressures on drug prices.
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